Location: Conowingo Rd and Rock Springs Rd, Conowingo, Cecil Cty Just after MD 222, we’ll approach US 222. At the light, follow 222 north to Lancaster, Penna. Location: Conowingo Rd and Rock Springs Rd, Conowingo, Cecil Cty Turn left for US 222 north. This is its southern terminus.  N to MD-591, S to MD-623  N … Continue reading U.S. Route 1, MD-222 to US-222